CATH Classification

Domain Context

CATH Clusters

Superfamily 2.80.10.50
Functional Family

Enzyme Information

3.4.24.69
Bontoxilysin.
based on mapping to UniProt P10844
Limited hydrolysis of proteins of the neuroexocytosis apparatus, synaptobrevins, SNAP25 or syntaxin. No detected action on small molecule substrates.
-!- Belongs to peptidase family M27.

UniProtKB Entries (2)

P29101
SYT2_RAT
Rattus norvegicus
Synaptotagmin-2
P10844
BXB_CLOBO
Clostridium botulinum
Botulinum neurotoxin type B

PDB Structure

PDB 2NM1
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Botulinum neurotoxin B recognizes its protein receptor with high affinity and specificity.
Jin, R., Rummel, A., Binz, T., Brunger, A.T.
Nature
CATH-Gene3D is a Global Biodata Core Resource Learn more...