CATH Domain 2moeA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.890	Methyl-cpg-binding Protein 2; Chain A
	3.30.890.10	Methyl-cpg-binding Protein 2; Chain A

Domain Context

CATH Clusters

Superfamily	Methyl-cpg-binding Protein 2; Chain A
Functional Family

Enzyme Information

3.2.2.-

Hydrolyzing N-glycosyl compounds.

based on mapping to UniProt O95243

UniProtKB Entries (1)

MBD4_HUMAN

Homo sapiens

Methyl-CpG-binding domain protein 4

PDB Structure

PDB	2MOE
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism
Primary Citation	Solution structure and intramolecular exchange of methyl-cytosine binding domain protein 4 (MBD4) on DNA suggests a mechanism to scan for mCpG/TpG mismatches. Walavalkar, N.M., Cramer, J.M., Buchwald, W.A., Scarsdale, J.N., Williams, D.C. Nucleic Acids Res.