CATH Domain 2mbrA01

Level	CATH Code	Description
	3	Alpha Beta
	3.90	Alpha-Beta Complex
	3.90.78	Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 1
	3.90.78.10	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain

Superfamily	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain
Functional Family	UDP-N-acetylenolpyruvoylglucosamine reductase

1.3.1.98

UDP-N-acetylmuramate dehydrogenase.

based on mapping to UniProt P08373

UDP-N-acetyl-alpha-D-muramate + NADP(+) = UDP-N-acetyl-3- O-(1-carboxyvinyl)-alpha-D-glucosamine + NADPH.

-!- NADH can to a lesser extent replace NADPH. -!- Formerly EC 1.1.1.158.

MURB_ECOLI

Escherichia coli K-12

UDP-N-acetylenolpyruvoylglucosamine reductase

PDB	2MBR
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	X-ray crystal structures of the S229A mutant and wild-type MurB in the presence of the substrate enolpyruvyl-UDP-N-acetylglucosamine at 1.8-A resolution. Benson, T.E., Walsh, C.T., Hogle, J.M. Biochemistry