CATH Domain 2m14A00

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.30	Roll
	2.30.29	PH-domain like
	2.30.29.30	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)

Domain Context

CATH Clusters

Superfamily	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Functional Family	Transcription initiation factor TFIIH subunit

Enzyme Information

UniProtKB Entries (1)

TFB1_YEAST

Saccharomyces cerevisiae S288C

General transcription and DNA repair factor IIH subunit TFB1

PDB Structure

PDB	2M14
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism
Primary Citation	Structural and functional evidence that Rad4 competes with Rad2 for binding to the Tfb1 subunit of TFIIH in NER. Lafrance-Vanasse, J., Arseneault, G., Cappadocia, L., Legault, P., Omichinski, J.G. Nucleic Acids Res.