CATH Domain 2lydA00

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.30	Roll
	2.30.29	PH-domain like
	2.30.29.30	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)

Domain Context

CATH Clusters

Superfamily	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Functional Family	mRNA-decapping enzyme 1B

Enzyme Information

UniProtKB Entries (1)

E1JJR3_DROME

Drosophila melanogaster

5'-3' exoribonuclease 1

PDB Structure

PDB	2LYD
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism
Primary Citation	A direct interaction between DCP1 and XRN1 couples mRNA decapping to 5' exonucleolytic degradation. Braun, J.E., Truffault, V., Boland, A., Huntzinger, E., Chang, C.T., Haas, G., Weichenrieder, O., Coles, M., Izaurralde, E. Nat.Struct.Mol.Biol.