1 keywords

CATH Domain 2ltbA00

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.30 Roll
Topology 2.30.180 FAS1 domain
Homologous Superfamily 2.30.180.10 FAS1 domain

Domain Context

CATH Clusters

Superfamily FAS1 domain
Functional Family Transforming growth factor-beta-induced protein ig-h3

Enzyme Information

UniProtKB Entries (1)

Q15582
BGH3_HUMAN
Homo sapiens
Transforming growth factor-beta-induced protein ig-h3

PDB Structure

PDB 2LTB
External Links
Method SOLUTION NMR
Organism
Primary Citation
Mutation in transforming growth factor beta induced protein associated with granular corneal dystrophy type 1 reduces the proteolytic susceptibility through local structural stabilization.
Underhaug, J., Kolds, H., Runager, K., Nielsen, J.T., Srensen, C.S., Kristensen, T., Otzen, D.E., Karring, H., Malmendal, A., Schitt, B., Enghild, J.J., Nielsen, N.C.
Biochim.Biophys.Acta