CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.1370 | Ribosomal Protein S8; Chain: A, domain 1 |
|
3.30.1370.50 | R3H-like domain |
Domain Context
CATH Clusters
| Superfamily | R3H-like domain |
| Functional Family | Immunoglobulin mu DNA-binding protein 2 |
Enzyme Information
| 3.6.4.13 |
RNA helicase.
based on mapping to UniProt P38935
ATP + H(2)O = ADP + phosphate.
-!- RNA helicases utilize the energy from ATP hydrolysis to unwind RNA. -!- Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity. -!- Some helicases unwind DNA as well as RNA. -!- May be identical with EC 3.6.4.12 (DNA helicase).
|
| 3.6.4.12 |
DNA helicase.
based on mapping to UniProt P38935
ATP + H(2)O = ADP + phosphate.
-!- DNA helicases utilize the energy from ATP hydrolysis to unwind double-stranded DNA. -!- Some of them unwind duplex DNA with a 3' to 5' polarity (1,3,5,8), other show 5' to 3' polarity (10,11,12,13) or unwind DNA in both directions (14,15). -!- Some helicases unwind DNA as well as RNA (4,9). -!- May be identical with EC 3.6.4.13 (RNA helicase).
|
UniProtKB Entries (1)
| P38935 |
SMBP2_HUMAN
Homo sapiens
DNA-binding protein SMUBP-2
|
PDB Structure
| PDB | 2LRR |
| External Links | |
| Method | SOLUTION NMR |
| Organism | |
| Primary Citation |
Structural Basis for 5'-End-Specific Recognition of Single-Stranded DNA by the R3H Domain from Human Smubp-2
J.Mol.Biol.
|
