CATH Classification

Domain Context

CATH Clusters

Superfamily Nucleotidyltransferases domain 2
Functional Family focal adhesion kinase 1 isoform X1

Enzyme Information

2.7.10.2
Non-specific protein-tyrosine kinase.
based on mapping to UniProt Q00944
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
-!- Unlike EC 2.7.10.1, this protein-tyrosine kinase does not have a transmembrane domain. -!- In the human genome, 32 non-specific protein-tyrosine kinases have been identified and these can be divided into 10 families. -!- Formerly EC 2.7.1.112.

UniProtKB Entries (1)

P49024
PAXI_CHICK
Gallus gallus
Paxillin

PDB Structure

PDB 2L6G
External Links
Method SOLUTION NMR
Organism
Primary Citation
Fat-Ld2 Double Labeled Construct with Free Ld4 Peptide
Bertolucci, C.M., Guibao, C., Zheng, J.
To be Published
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