CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.40 | Beta Barrel |
|
2.40.128 | Lipocalin |
|
2.40.128.20 | Calycin beta-barrel core domain |
Domain Context
CATH Clusters
| Superfamily | 2.40.128.20 |
| Functional Family | Prostaglandin-H2 D-isomerase |
Enzyme Information
| 5.3.99.2 |
Prostaglandin-D synthase.
based on mapping to UniProt O09114
(5Z,13E,15S)-9-alpha,11-alpha-epidioxy-15-hydroxyprosta-5,13-dienoate = (5Z,13E,15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate.
-!- Brings about the opening of the epidioxy bridge.
|
UniProtKB Entries (1)
| O09114 |
PTGDS_MOUSE
Mus musculus
Prostaglandin-H2 D-isomerase
|
PDB Structure
| PDB | 2KTD |
| External Links | |
| Method | SOLUTION NMR |
| Organism | |
| Primary Citation |
Solution Structure of Lipocalin-type Prostaglandin D synthase / Substrate analog complex reveals Open-Closed Conformational Change required for Substrate Recognition
To be Published
|
