CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.40 | Herpes Virus-1 |
|
3.30.40.10 | Zinc/RING finger domain, C3HC4 (zinc finger) |
Domain Context
CATH Clusters
| Superfamily | Zinc/RING finger domain, C3HC4 (zinc finger) |
| Functional Family | Lysine (K)-specific demethylase 5A |
Enzyme Information
| 1.14.11.- |
With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors.
based on mapping to UniProt P29375
|
UniProtKB Entries (1)
| P29375 |
KDM5A_HUMAN
Homo sapiens
Lysine-specific demethylase 5A
|
PDB Structure
| PDB | 2KGI |
| External Links | |
| Method | SOLUTION NMR |
| Organism | |
| Primary Citation |
Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger.
Nature
|
