CATH Classification

Domain Context

CATH Clusters

Superfamily lambda repressor-like DNA-binding domains
Functional Family HTH-type transcriptional repressor PurR

Enzyme Information

UniProtKB Entries (1)

P03023
LACI_ECOLI
Escherichia coli K-12
Lactose operon repressor

PDB Structure

PDB 2KEK
External Links
Method SOLUTION NMR
Organism
Primary Citation
Specificity and affinity of Lac repressor for the auxiliary operators O2 and O3 are explained by the structures of their protein-DNA complexes.
Romanuka, J., Folkers, G.E., Biris, N., Tishchenko, E., Wienk, H., Bonvin, A.M., Kaptein, R., Boelens, R.
J.Mol.Biol.