CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.30 | Roll |
|
2.30.42 | Pdz3 Domain |
|
2.30.42.10 | PDZ domain |
Domain Context
CATH Clusters
| Superfamily | 2.30.42.10 |
| Functional Family | Segment polarity protein dishevelled homolog DVL-3 |
Enzyme Information
UniProtKB Entries (1)
| P51141 |
DVL1_MOUSE
Mus musculus
Segment polarity protein dishevelled homolog DVL-1
|
PDB Structure
| PDB | 2KAW |
| External Links | |
| Method | SOLUTION NMR |
| Organism | |
| Primary Citation |
Sulindac inhibits canonical Wnt signaling by blocking the PDZ domain of the protein Dishevelled.
Angew.Chem.Int.Ed.Engl.
|
