CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.30 | Roll |
|
2.30.29 | PH-domain like |
|
2.30.29.30 | Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) |
Domain Context
CATH Clusters
| Superfamily | Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) |
| Functional Family | Transcription initiation factor TFIIH subunit |
Enzyme Information
UniProtKB Entries (2)
| P04486 |
VP16_HHV1F
Human alphaherpesvirus 1 strain F
Tegument protein VP16
|
| P32776 |
TFB1_YEAST
Saccharomyces cerevisiae S288C
General transcription and DNA repair factor IIH subunit TFB1
|
PDB Structure
| PDB | 2K2U |
| External Links | |
| Method | SOLUTION NMR |
| Organism | Escherichia |
| Primary Citation |
NMR Structure of the Complex between the Tfb1 Subunit of TFIIH and the Activation Domain of VP16: Structural Similarities between VP16 and p53.
J.Am.Chem.Soc.
|