CATH Classification

Domain Context

CATH Clusters

Superfamily SET domain
Functional Family PR domain zinc finger protein 2

Enzyme Information

2.1.1.43
Histone-lysine N-methyltransferase.
based on mapping to UniProt Q13029
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].

UniProtKB Entries (1)

Q13029
PRDM2_HUMAN
Homo sapiens
PR domain zinc finger protein 2

PDB Structure

PDB 2JV0
External Links
Method SOLUTION NMR
Organism Escherichia
Primary Citation
Structural studies of the SET domain from RIZ1 tumor suppressor
Briknarova, K., Zhou, X., Satterthwait, A., Hoyt, D.W., Ely, K.R., Huang, S.
Biochem.Biophys.Res.Commun.