CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.20 | Up-down Bundle | |
1.20.58 | Methane Monooxygenase Hydroxylase; Chain G, domain 1 | |
1.20.58.80 | Phosphotransferase system, lactose/cellobiose-type IIA subunit |
Domain Context
CATH Clusters
Superfamily | Phosphotransferase system, lactose/cellobiose-type IIA subunit |
Functional Family | Vacuolar protein sorting-associated protein 4A |
Enzyme Information
3.6.4.6 |
Vesicle-fusing ATPase.
based on mapping to UniProt Q9UN37
ATP + H(2)O = ADP + phosphate.
-!- A large family of ATP-hydrolyzing enzymes involved in the heterotypic fusion of membrane vesicles with target membranes and the homotypic fusion of various membrane compartments. -!- They belong to the AAA-type (ATPase associated with a variety of cell activities) ATPase superfamily. -!- They include peroxin, which apparently is involved in Zellweger's syndrome.
|
UniProtKB Entries (1)
Q9UN37 |
VPS4A_HUMAN
Homo sapiens
Vacuolar protein sorting-associated protein 4A
|
PDB Structure
PDB | 2JQ9 |
External Links | |
Method | SOLUTION NMR |
Organism | Escherichia |
Primary Citation |
ESCRT-III recognition by VPS4 ATPases.
Nature
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