CATH Domain 2jlfA02

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.490	Globin-like
	1.10.490.60	Phage p2 RNA dependent RNA polymerase domain

Domain Context

CATH Clusters

Superfamily	Phage p2 RNA dependent RNA polymerase domain
Functional Family

Enzyme Information

2.7.7.48

RNA-directed RNA polymerase.

based on mapping to UniProt P11124

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).

-!- Catalyzes RNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. -!- Can initiate a chain de novo. -!- See also EC 2.7.7.6.

UniProtKB Entries (1)

P11124

RDRP_BPPH6

Pseudomonas virus phi6

RNA-directed RNA polymerase

PDB Structure

PDB	2JLF
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural Explanation for the Role of Mn2+ in the Activity of {Phi}6 RNA-Dependent RNA Polymerase. Poranen, M.M., Salgado, P.S., Koivunen, M.R.L., Wright, S., Bamford, D.H., Stuart, D.I., Grimes, J.M. Nucleic Acids Res.