CATH Domain 2jihA01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.390	Collagenase (Catalytic Domain)
	3.40.390.10	Collagenase (Catalytic Domain)

Domain Context

CATH Clusters

Superfamily	Collagenase (Catalytic Domain)
Functional Family	A disintegrin and metalloproteinase with thrombospondin motifs 1

Enzyme Information

3.4.24.-

Metalloendopeptidases.

based on mapping to UniProt Q9UHI8

UniProtKB Entries (1)

ATS1_HUMAN

Homo sapiens

A disintegrin and metalloproteinase with thrombospondin motifs 1

PDB Structure

PDB	2JIH
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal structures of human ADAMTS-1 reveal a conserved catalytic domain and a disintegrin-like domain with a fold homologous to cysteine-rich domains. Gerhardt, S., Hassall, G., Hawtin, P., McCall, E., Flavell, L., Minshull, C., Hargreaves, D., Ting, A., Pauptit, R.A., Parker, A.E., Abbott, W.M. J. Mol. Biol.