CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.50 | Alpha/alpha barrel |
|
1.50.10 | Glycosyltransferase |
|
1.50.10.10 |
Domain Context
CATH Clusters
| Superfamily | 1.50.10.10 |
| Functional Family | Cytoplasmic trehalase |
Enzyme Information
| 3.2.1.28 |
Alpha,alpha-trehalase.
based on mapping to UniProt P13482
Alpha,alpha-trehalose + H(2)O = beta-D-glucose + alpha-D-glucose.
-!- The enzyme is an anomer-inverting glucosidase that catalyzes the hydrolysis of the alpha-glucosidic O-linkage of alpha,alpha- trehalose, releasing initially equimolar amounts of alpha- and beta- D-glucose. -!- It is widely distributed in microorganisms, plants, invertebrates and vertebrates.
|
UniProtKB Entries (1)
| P13482 |
TREA_ECOLI
Escherichia coli K-12
Periplasmic trehalase
|
PDB Structure
| PDB | 2JG0 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Molecular Basis for Trehalase Inhibition Revealed by the Structure of Trehalase in Complex with Potent Inhibitors.
Angew.Chem.Int.Ed.Engl.
|
