CATH Classification

Domain Context

CATH Clusters

Superfamily B-lactam Antibiotic, Isopenicillin N Synthase; Chain
Functional Family

Enzyme Information

1.14.20.1
Deacetoxycephalosporin-C synthase.
based on mapping to UniProt P18548
Penicillin N + 2-oxoglutarate + O(2) = deacetoxycephalosporin C + succinate + CO(2) + H(2)O.
-!- Forms part of the penicillin biosynthesis pathway.

UniProtKB Entries (1)

P18548
CEFE_STRC2
Streptomyces clavuligerus ATCC 27064
Deacetoxycephalosporin C synthase

PDB Structure

PDB 2JB8
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Study of the Oxidative Half-Reaction Catalysed by a Non-Heme Ferrous Catalytic Centre by Means of Structural and Computational Methodologies
Cicero, G., Carbonera, C., Valegard, K., Hajdu, J., Andersson, I., Ranghino, G.
Int.J.Quantum Chem.