CATH Domain 2jamA02

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.510	Transferase(Phosphotransferase); domain 1
	1.10.510.10	Transferase(Phosphotransferase) domain 1

Domain Context

CATH Clusters

Superfamily	Transferase(Phosphotransferase) domain 1
Functional Family	Calcium/calmodulin-dependent protein kinase type 1

Enzyme Information

2.7.11.17

Calcium/calmodulin-dependent protein kinase.

based on mapping to UniProt Q96NX5

ATP + a protein = ADP + a phosphoprotein.

-!- Requires calmodulin. -!- A wide range of proteins can act as acceptor, including vimentin, synapsin, glycogen synthase, myosin light-chains and the microtubule- associated tau protein. -!- Not identical with EC 2.7.11.18 or EC 2.7.11.26. -!- Formerly EC 2.7.1.120 and EC 2.7.1.123.

UniProtKB Entries (1)

Q96NX5

KCC1G_HUMAN

Homo sapiens

Calcium/calmodulin-dependent protein kinase type 1G

PDB Structure

PDB	2JAM
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal Structure of Human Calmodulin-Dependent Protein Kinase I G Debreczeni, J.E., Bullock, A., Keates, T., Niesen, F.H., Salah, E., Shrestha, L., Smee, C., Sobott, F., Pike, A.C.W., Bunkoczi, G., von Delft, F., Turnbull, A., Weigelt, J., Arrowsmith, C.H., Edwards, A., Sundstrom, M., Knapp, S. To be Published