CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.226 | 2-enoyl-CoA Hydratase; Chain A, domain 1 |
|
3.90.226.10 | 2-enoyl-CoA Hydratase; Chain A, domain 1 |
Domain Context
CATH Clusters
| Superfamily | 2-enoyl-CoA Hydratase; Chain A, domain 1 |
| Functional Family | p-hydroxycinnamoyl CoA hydratase/lyase |
Enzyme Information
| 4.2.1.101 |
Trans-feruloyl-CoA hydratase.
based on mapping to UniProt O69762
4-hydroxy-3-methoxyphenyl-beta-hydroxypropanoyl-CoA = feruloyl-CoA + H(2)O.
|
| 4.1.2.41 |
Vanillin synthase.
based on mapping to UniProt O69762
3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propanoyl-CoA = vanillin + acetyl- CoA.
-!- Involved, together with EC 4.2.1.101 in the production of vanillin from trans-ferulic acid. -!- Vanillin is converted to vanillate by EC 1.2.1.67.
|
UniProtKB Entries (1)
| O69762 |
HCHL_PSEFL
Pseudomonas fluorescens
Hydroxycinnamoyl-CoA hydratase-lyase
|
PDB Structure
| PDB | 2J5I |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The 1.8 A Resolution Structure of Hydroxycinnamoyl- Coenzyme a Hydratase-Lyase (Hchl) from Pseudomonas Fluorescens, an Enzyme that Catalyses the Transformation of Feruloyl-Coenzyme a to Vanillin.
Acta Crystallogr.,Sect.D
|