CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.20 | Up-down Bundle |
|
1.20.80 | Acyl-CoA Binding Protein |
|
1.20.80.10 |
Domain Context
CATH Clusters
| Superfamily | 1.20.80.10 |
| Functional Family | Protein-tyrosine kinase 2-beta isoform 1 |
Enzyme Information
| 2.7.10.2 |
Non-specific protein-tyrosine kinase.
based on mapping to UniProt Q00944
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
-!- Unlike EC 2.7.10.1, this protein-tyrosine kinase does not have a transmembrane domain. -!- In the human genome, 32 non-specific protein-tyrosine kinases have been identified and these can be divided into 10 families. -!- Formerly EC 2.7.1.112.
|
UniProtKB Entries (1)
| Q00944 |
FAK1_CHICK
Gallus gallus
Focal adhesion kinase 1
|
PDB Structure
| PDB | 2J0J |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural Basis for the Autoinhibition of Focal Adhesion Kinase
Cell(Cambridge,Mass.)
|
