CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.30 | 2-Layer Sandwich | |
3.30.56 | Phenylalanyl-tRNA Synthetase; Chain B, domain 1 | |
3.30.56.10 |
Domain Context
CATH Clusters
Superfamily | 3.30.56.10 |
Functional Family |
Enzyme Information
6.1.1.20 |
Phenylalanine--tRNA ligase.
based on mapping to UniProt Q5SGX1
ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl- tRNA(Phe).
|
UniProtKB Entries (1)
Q5SGX2 |
SYFA_THET8
Thermus thermophilus HB8
Phenylalanine--tRNA ligase alpha subunit
|
PDB Structure
PDB | 2IY5 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
The crystal structure of the ternary complex of phenylalanyl-tRNA synthetase with tRNAPhe and a phenylalanyl-adenylate analogue reveals a conformational switch of the CCA end.
Biochemistry
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