CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family Serine/threonine-protein kinase

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt Q9P1W9
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

Q9P1W9
PIM2_HUMAN
Homo sapiens
Serine/threonine-protein kinase pim-2

PDB Structure

PDB 2IWI
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of the PIM2 kinase in complex with an organoruthenium inhibitor.
Bullock, A.N., Russo, S., Amos, A., Pagano, N., Bregman, H., Debreczeni, J.E., Lee, W.H., von Delft, F., Meggers, E., Knapp, S.
PLoS ONE
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