CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.150 | Vaccinia Virus protein VP39 |
Domain Context
CATH Clusters
| Superfamily | Vaccinia Virus protein VP39 |
| Functional Family | Phenazine-specific methyltransferase |
Enzyme Information
| 2.1.1.327 |
Phenazine-1-carboxylate N-methyltransferase.
based on mapping to UniProt Q9HWH2
S-adenosyl-L-methionine + phenazine-1-carboxylate = S-adenosyl-L- homocysteine + 5-methylphenazine-1-carboxylate.
-!- The enzyme, characterized from the bacterium Pseudomonas aeruginosa, is involved in the biosynthesis of pyocyanin, a toxin produced and secreted by the organism. -!- The enzyme is active in vitro only in the presence of EC 1.14.13.218.
|
UniProtKB Entries (1)
| Q9HWH2 |
PHZM_PSEAE
Pseudomonas aeruginosa PAO1
Phenazine-1-carboxylate N-methyltransferase
|
PDB Structure
| PDB | 2IP2 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structural and functional analysis of the pyocyanin biosynthetic protein PhzM from Pseudomonas aeruginosa.
Biochemistry
|