CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.1740 | 2',3'-cyclic nucleotide 3'-phosphodiesterase fold |
|
3.90.1740.10 | 2',3'-cyclic nucleotide 3'-phosphodiesterase superfamily |
Domain Context
CATH Clusters
| Superfamily | 2',3'-cyclic nucleotide 3'-phosphodiesterase superfamily |
| Functional Family | Tetratricopeptide repeat protein 25 |
Enzyme Information
| 3.1.4.37 |
2',3'-cyclic-nucleotide 3'-phosphodiesterase.
based on mapping to UniProt P13233
Nucleoside 2',3'-cyclic phosphate + H(2)O = nucleoside 2'-phosphate.
-!- The brain enzyme acts on 2',3'-cyclic AMP more rapidly than on the UMP or CMP derivatives. -!- An enzyme from liver acts on 2',3'-cyclic CMP more rapidly than on the purine derivatives; it also hydrolyzes the corresponding 3',5'-cyclic phosphates, more slowly. -!- This latter enzyme has been called cyclic-CMP phosphodiesterase.
|
UniProtKB Entries (1)
| P13233 |
CN37_RAT
Rattus norvegicus
2',3'-cyclic-nucleotide 3'-phosphodiesterase
|
PDB Structure
| PDB | 2ILX |
| External Links | |
| Method | SOLUTION NMR |
| Organism | Escherichia |
| Primary Citation |
Solution structure of the catalytic domain of RICH protein from goldfish.
Febs J.
|