1 keywords

CATH Domain 2ik8B02

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.167 Regulator of G-protein Signalling 4; domain 2
Homologous Superfamily 1.10.167.10 Regulator of G-protein Signalling 4, domain 2

Domain Context

CATH Clusters

Superfamily Regulator of G-protein Signalling 4, domain 2
Functional Family Putative regulator of g-protein signaling 12

Enzyme Information

UniProtKB Entries (1)

O15492
RGS16_HUMAN
Homo sapiens
Regulator of G-protein signaling 16

PDB Structure

PDB 2IK8
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Soundararajan, M., Willard, F.S., Kimple, A.J., Turnbull, A.P., Ball, L.J., Schoch, G.A., Gileadi, C., Fedorov, O.Y., Dowler, E.F., Higman, V.A., Hutsell, S.Q., Sundstrom, M., Doyle, D.A., Siderovski, D.P.
Proc.Natl.Acad.Sci.Usa