CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.220 | Adenine-n6-DNA-methyltransferase TaqI; Chain A, domain 2 |
|
3.90.220.10 | Adenine-n6-DNA-methyltransferase Taqi, Chain A, domain 2 |
Domain Context
CATH Clusters
| Superfamily | Adenine-n6-DNA-methyltransferase Taqi, Chain A, domain 2 |
| Functional Family |
Enzyme Information
| 2.1.1.72 |
Site-specific DNA-methyltransferase (adenine-specific).
based on mapping to UniProt P14385
S-adenosyl-L-methionine + adenine in DNA = S-adenosyl-L-homocysteine + N-6-methyladenine in DNA.
-!- This is a large group of enzymes, most of which form so-called 'restriction-modification systems', with nucleases that possess similar site specificity (the nucleases are listed as either EC 3.1.21.3, EC 3.1.21.4 and EC 3.1.21.5). -!- See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/
|
UniProtKB Entries (1)
| P14385 |
MTTA_THEAQ
Thermus aquaticus
Modification methylase TaqI
|
PDB Structure
| PDB | 2IBT |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
2-Aminopurine Flipped into the Active Site of the Adenine-Specific DNA Methyltransferase M.TaqI: Crystal Structures and Time-Resolved Fluorescence
J.Am.Chem.Soc.
|
