CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.20 |
Domain Context
CATH Clusters
| Superfamily | 3.40.50.20 |
| Functional Family | D-alanine--D-alanine ligase |
Enzyme Information
| 6.3.2.4 |
D-alanine--D-alanine ligase.
based on mapping to UniProt Q5HEB7
ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine.
-!- Involved with EC 6.3.2.7 or EC 6.3.2.13, EC 6.3.2.8, EC 6.3.2.9 and EC 6.3.2.10 in the synthesis of a cell-wall peptide.
|
UniProtKB Entries (1)
| Q5HEB7 |
DDL_STAAC
Staphylococcus aureus subsp. aureus COL
D-alanine--D-alanine ligase
|
PDB Structure
| PDB | 2I80 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Allosteric inhibition of Staphylococcus aureus D-alanine:D-alanine ligase revealed by crystallographic studies.
Proc.Natl.Acad.Sci.Usa
|
