CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.10 | Roll |
|
3.10.490 | Hypothetical upf0131 protein ytfp |
|
3.10.490.10 | Gamma-glutamyl cyclotransferase-like |
Domain Context
CATH Clusters
| Superfamily | Gamma-glutamyl cyclotransferase-like |
| Functional Family | Gamma-glutamylcyclotransferase |
Enzyme Information
| 4.3.2.9 |
Gamma-glutamylcyclotransferase.
based on mapping to UniProt O75223
Alpha-(gamma-L-glutamyl)-L-amino acid = alpha-L-amino acid + 5-oxo-L- proline.
-!- The enzyme, found in animals and plants, acts on derivatives of L-glutamate, L-2-aminobutanoate, L-alanine and glycine. -!- The enzyme acts as a cyclotransferase, cleaving the amide bond via transamidation using the alpha-amine of the L-glutamyl residue, releasing it as the cyclic 5-oxo-L-proline. -!- Formerly EC 2.3.2.4.
|
UniProtKB Entries (1)
| O75223 |
GGCT_HUMAN
Homo sapiens
Gamma-glutamylcyclotransferase
|
PDB Structure
| PDB | 2I5T |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of Homo sapiens protein LOC79017.
Proteins
|
