CATH Classification

Domain Context

CATH Clusters

Superfamily HIV Type 1 Reverse Transcriptase, subunit A, domain 1
Functional Family Gag-Pol polyprotein

Enzyme Information

UniProtKB Entries (2)

P03366
POL_HV1B1
Human immunodeficiency virus type 1 BH10
Gag-Pol polyprotein
Q8UM83
Q8UM83_9HIV1
Human immunodeficiency virus 1
Pol protein

PDB Structure

PDB 2I5J
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
HIV-1 reverse transcriptase structure with RNase H inhibitor dihydroxy benzoyl naphthyl hydrazone bound at a novel site.
Himmel, D.M., Sarafianos, S.G., Dharmasena, S., Hossain, M.M., McCoy-Simandle, K., Ilina, T., Clark, A.D., Knight, J.L., Julias, J.G., Clark, P.K., Krogh-Jespersen, K., Levy, R.M., Hughes, S.H., Parniak, M.A., Arnold, E.
Acs Chem.Biol.