CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.20 | Alpha-Beta Barrel |
|
3.20.20 | TIM Barrel |
|
3.20.20.70 | Aldolase class I |
Domain Context
CATH Clusters
| Superfamily | Aldolase class I |
| Functional Family |
Enzyme Information
| 2.8.1.10 |
Thiazole synthase.
based on mapping to UniProt Q5SKG7
1-deoxy-D-xylulose 5-phosphate + 2-iminoacetate + thiocarboxy-[sulfur- carrier protein ThiS] = 2-((2R,5Z)-2-carboxy-4-methylthiazol-5(2H)- ylidene)ethyl phosphate + [sulfur-carrier protein ThiS] + 2 H(2)O.
-!- H(2)S can provide the sulfur in vitro. -!- Part of the pathway for thiamine biosynthesis.
|
UniProtKB Entries (2)
| Q5SKG7 |
THIG_THET8
Thermus thermophilus HB8
Thiazole synthase
|
| Q72KL7 |
THIS_THET2
Thermus thermophilus HB27
Sulfur carrier protein ThiS
|
PDB Structure
| PDB | 2HTM |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of TTHA0676 from Thermus thermophilus HB8
To be Published
|