CATH Classification

Domain Context

CATH Clusters

Superfamily Acid Proteases
Functional Family Gag-Pol polyprotein

Enzyme Information

UniProtKB Entries (1)

Q7SSI0
Q7SSI0_9HIV1
Human immunodeficiency virus 1
Protease

PDB Structure

PDB 2HS2
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Ultra-high Resolution Crystal Structure of HIV-1 Protease Mutant Reveals Two Binding Sites for Clinical Inhibitor TMC114.
Kovalevsky, A.Y., Liu, F., Leshchenko, S., Ghosh, A.K., Louis, J.M., Harrison, R.W., Weber, I.T.
J.Mol.Biol.