CATH Domain 2hmjA01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.90	Alpha-Beta Complex
	3.90.380	Naphthalene 1,2-dioxygenase Alpha Subunit; Chain A, domain 1
	3.90.380.10	Naphthalene 1,2-dioxygenase Alpha Subunit; Chain A, domain 1

Domain Context

CATH Clusters

Superfamily	Naphthalene 1,2-dioxygenase Alpha Subunit; Chain A, domain 1
Functional Family	Naphthalene 1,2-dioxygenase system, large oxygenase component

Enzyme Information

1.14.12.12

Naphthalene 1,2-dioxygenase.

based on mapping to UniProt P0A111

Naphthalene + NADH + O(2) = (1R,2S)-1,2-dihydronaphthalene-1,2-diol + NAD(+).

-!- Comprises a multicomponent system, containing a reductase that is an iron-sulfur flavoprotein (FAD; EC 1.18.1.3), an iron-sulfur oxygenase, and ferredoxin.

UniProtKB Entries (1)

P0A111

NDOB_PSEU8

Pseudomonas sp. C18

Naphthalene 1,2-dioxygenase system, large oxygenase component

PDB Structure

PDB	2HMJ
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Structural basis for regioselectivity and stereoselectivity of product formation by naphthalene 1,2-dioxygenase. Ferraro, D.J., Okerlund, A.L., Mowers, J.C., Ramaswamy, S. J.Bacteriol.