CATH Classification

Domain Context

CATH Clusters

Superfamily LuxQ periplasmic domain, C-terminal subdomain
Functional Family Autoinducer 2 sensor kinase/phosphatase LuxQ

Enzyme Information

2.7.13.3
Histidine kinase.
based on mapping to UniProt P54302
ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.
-!- This entry has been included to accommodate those protein-histidine kinases for which the phosphorylation site has not been established (i.e. either the pros- or tele-nitrogen of histidine). -!- A number of histones can act as acceptor.
3.1.3.-
Phosphoric monoester hydrolases.
based on mapping to UniProt P54302

UniProtKB Entries (1)

P54300
LUXP_VIBHA
Vibrio harveyi
Autoinducer 2-binding periplasmic protein LuxP

PDB Structure

PDB 2HJ9
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Ligand-induced asymmetry in histidine sensor kinase complex regulates quorum sensing.
Neiditch, M.B., Federle, M.J., Pompeani, A.J., Kelly, R.C., Swem, D.L., Jeffrey, P.D., Bassler, B.L., Hughson, F.M.
Cell(Cambridge,Mass.)
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