CATH Classification

Domain Context

CATH Clusters

Superfamily Calcium-transporting ATPase, cytoplasmic transduction domain A
Functional Family Copper-transporting ATPase 1, putative

Enzyme Information

7.2.2.8
P-type Cu(+) transporter.
based on mapping to UniProt O29777
ATP + H(2)O + Cu(+)(Side 1) = ADP + phosphate + Cu(+)(Side 2).
-!- A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. -!- This enzyme transports Cu(+) or Ag(+), and cannot transport the divalent ions, contrary to EC 7.2.2.9, which mainly transports the divalent copper ion. -!- Formerly EC 3.6.3.54.

UniProtKB Entries (1)

O29777
COPA_ARCFU
Archaeoglobus fulgidus DSM 4304
Probable copper-exporting P-type ATPase

PDB Structure

PDB 2HC8
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure of the Actuator Domain from the Archaeoglobus fulgidus Cu(+)-ATPase(,).
Sazinsky, M.H., Agarwal, S., Rosenzweig, A.C.
Biochemistry
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