CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.47 | Peroxisomal Thiolase; Chain A, domain 1 |
|
3.40.47.10 | Thiolase/Chalcone synthase |
Domain Context
CATH Clusters
| Superfamily | 3.40.47.10 |
| Functional Family | Chalcone synthase 2 |
Enzyme Information
| 2.3.1.74 |
Chalcone synthase.
based on mapping to UniProt Q55E72
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO(2).
-!- The enzyme catalyzes the first committed step in the biosynthesis of flavonoids. -!- It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
|
| 2.3.1.- |
Transferring groups other than amino-acyl groups.
based on mapping to UniProt Q55E72
|
UniProtKB Entries (1)
| Q55E72 |
PKS1_DICDI
Dictyostelium discoideum
Probable polyketide synthase 1
|
PDB Structure
| PDB | 2H84 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Biosynthesis of Dictyostelium discoideum differentiation-inducing factor by a hybrid type I fatty acid-type III polyketide synthase.
Nat.Chem.Biol.
|
