CATH Domain 2gz8A03

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.1840	main proteinase (3clpro) structure, domain 3
	1.10.1840.10	main proteinase (3clpro) structure, domain 3

Domain Context

CATH Clusters

Superfamily	main proteinase (3clpro) structure, domain 3
Functional Family	Replicase polyprotein 1a

Enzyme Information

UniProtKB Entries (1)

Q692E5_CVHSA

SARS coronavirus TJF

Orf1a polyprotein

PDB Structure

PDB	2GZ8
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Structure-Based Drug Design and Structural Biology Study of Novel Nonpeptide Inhibitors of Severe Acute Respiratory Syndrome Coronavirus Main Protease Lu, I.L., Mahindroo, N., Liang, P.H., Peng, Y.H., Kuo, C.J., Tsai, K.C., Hsieh, H.P., Chao, Y.S., Wu, S.Y. J.Med.Chem.