CATH Classification

Domain Context

CATH Clusters

Superfamily Ribonuclease H-like superfamily/Ribonuclease H
Functional Family DNA polymerase III subunit epsilon

Enzyme Information

2.7.7.7
DNA-directed DNA polymerase.
based on mapping to UniProt P03007
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.

UniProtKB Entries (1)

P03007
DPO3E_ECOLI
Escherichia coli K-12
DNA polymerase III subunit epsilon

PDB Structure

PDB 2GUI
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure and Function of Cyclized Versions of the Proofreading Exonuclease Subunit E. coli DNA Polymerase III
Park, A.Y., Carr, P.D., Oliis, D.L., Dixon, N.E.
To be Published
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