CATH Domain 2gquA03

Level	CATH Code	Description
	3	Alpha Beta
	3.90	Alpha-Beta Complex
	3.90.78	Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 1
	3.90.78.10	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain

Superfamily	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain
Functional Family

1.3.1.98

UDP-N-acetylmuramate dehydrogenase.

based on mapping to UniProt Q5SJC8

UDP-N-acetyl-alpha-D-muramate + NADP(+) = UDP-N-acetyl-3- O-(1-carboxyvinyl)-alpha-D-glucosamine + NADPH.

-!- NADH can to a lesser extent replace NADPH. -!- Formerly EC 1.1.1.158.

MURB_THET8

Thermus thermophilus HB8

UDP-N-acetylenolpyruvoylglucosamine reductase

PDB	2GQU
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Crystal structure of UDP-N-acetylenolpyruvylglucosamine reductase (MurB) from Thermus caldophilus Kim, M.-K., Cho, M.K., Song, H.-E., Kim, D., Park, B.-H., Lee, J.H., Kang, G.B., Kim, S.H., Im, Y.J., Lee, D.-S., Eom, S.H. Proteins