CATH Domain 2giuA00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.565	Retinoid X Receptor
	1.10.565.10	Retinoid X Receptor

Domain Context

CATH Clusters

Superfamily	Retinoid X Receptor
Functional Family	Estrogen receptor

Enzyme Information

UniProtKB Entries (1)

ESR2_HUMAN

Homo sapiens

Estrogen receptor beta

PDB Structure

PDB	2GIU
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	The discovery of tetrahydrofluorenones as a new class of estrogen receptor beta-subtype selective ligands. Wilkening, R.R., Ratcliffe, R.W., Tynebor, E.C., Wildonger, K.J., Fried, A.K., Hammond, M.L., Mosley, R.T., Fitzgerald, P.M.D., Sharma, N., McKeever, B.M., Nilsson, S., Carlquist, M., Thorsell, A., Locco, L., Katz, R., Frisch, K., Birzin, E.T., Wilkinson, H.A., Mitra, S., Cai, S., Hayes, E.C., Schaeffer, J.M., Rohrer, S.P. Bioorg.Med.Chem.Lett.