CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.1370 | Ribosomal Protein S8; Chain: A, domain 1 |
|
3.30.1370.60 | Hypothetical oxidoreductase yiak; domain 2 |
Domain Context
CATH Clusters
| Superfamily | Hypothetical oxidoreductase yiak; domain 2 |
| Functional Family |
Enzyme Information
| 1.1.1.237 |
Hydroxyphenylpyruvate reductase.
based on mapping to UniProt P30178
(1) (R)-3-(4-hydroxyphenyl)lactate + NAD(P)(+) = 3-(4-hydroxyphenyl)pyruvate + NAD(P)H. (2) (R)-3-(3,4-dihydroxyphenyl)lactate + NAD(P)(+) = 3-(3,4- dihydroxyphenyl)pyruvate + NAD(P)H.
-!- The enzyme participates in the biosynthesis of rosmarinic acid. -!- It belongs to the family of D-isomer-specific 2-hydroxyacid dehydrogenases, and prefers NADPH to NADH.
|
| 1.1.1.- |
With NAD(+) or NADP(+) as acceptor.
based on mapping to UniProt P30178
|
UniProtKB Entries (1)
| P30178 |
HCXB_ECOLI
Escherichia coli K-12
Hydroxycarboxylate dehydrogenase B
|
PDB Structure
| PDB | 2G8Y |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
The structure of a putative malate/lactate dehydrogenase from E. coli.
To be Published
|
