1 keywords

CATH Domain 2fxdB00

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.40 Beta Barrel
Topology 2.40.70 Cathepsin D, subunit A; domain 1
Homologous Superfamily 2.40.70.10 Acid Proteases

Domain Context

CATH Clusters

Superfamily Acid Proteases
Functional Family Gag-Pol polyprotein

Enzyme Information

UniProtKB Entries (1)

Q90HG9
Q90HG9_9HIV1
Human immunodeficiency virus 1
Pol polyprotein

PDB Structure

PDB 2FXD
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
X-ray crystal structures of human immunodeficiency virus type 1 protease mutants complexed with atazanavir.
Klei, H.E., Kish, K., Lin, P.F., Guo, Q., Friborg, J., Rose, R.E., Zhang, Y., Goldfarb, V., Langley, D.R., Wittekind, M., Sheriff, S.
J.Virol.