CATH Domain 2fjmA00

Level	CATH Code	Description
	3	Alpha Beta
	3.90	Alpha-Beta Complex
	3.90.190	Protein-Tyrosine Phosphatase; Chain A
	3.90.190.10	Protein tyrosine phosphatase superfamily

Superfamily	Protein tyrosine phosphatase superfamily
Functional Family	Tyrosine-protein phosphatase non-receptor type 1

3.1.3.48

Protein-tyrosine-phosphatase.

based on mapping to UniProt P18031

Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.

-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

PTN1_HUMAN

Homo sapiens

Tyrosine-protein phosphatase non-receptor type 1

PDB	2FJM
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Conformation-assisted inhibition of protein-tyrosine phosphatase-1B elicits inhibitor selectivity over T-cell protein-tyrosine phosphatase. Asante-Appiah, E., Patel, S., Desponts, C., Taylor, J.M., Lau, C., Dufresne, C., Therien, M., Friesen, R., Becker, J.W., Leblanc, Y., Kennedy, B.P., Scapin, G. J.Biol.Chem.