CATH Classification

Domain Context

CATH Clusters

Superfamily HIT-like
Functional Family Fragile histidine triad

Enzyme Information

3.6.1.29
Bis(5'-adenosyl)-triphosphatase.
based on mapping to UniProt P49789
P(1)-P(3)-bis(5'-adenosyl) triphosphate + H(2)O = ADP + AMP.

UniProtKB Entries (1)

P49789
FHIT_HUMAN
Homo sapiens
Bis(5'-adenosyl)-triphosphatase

PDB Structure

PDB 2FHI
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Genetic, biochemical, and crystallographic characterization of Fhit-substrate complexes as the active signaling form of Fhit.
Pace, H.C., Garrison, P.N., Robinson, A.K., Barnes, L.D., Draganescu, A., Rosler, A., Blackburn, G.M., Siprashvili, Z., Croce, C.M., Huebner, K., Brenner, C.
Proc.Natl.Acad.Sci.USA