CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.40 | Beta Barrel |
|
2.40.50 | OB fold (Dihydrolipoamide Acetyltransferase, E2P) |
|
2.40.50.610 | Type II restriction enzyme SfiI, DNA-recognition domain |
Domain Context
CATH Clusters
| Superfamily | Type II restriction enzyme SfiI, DNA-recognition domain |
| Functional Family |
Enzyme Information
| 3.1.21.4 |
Type II site-specific deoxyribonuclease.
based on mapping to UniProt O52512
Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.
-!- Large group of enzymes which recognize specific short DNA sequences and cleave either within, or at a short specific distance from, the recognition site. -!- See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/
|
UniProtKB Entries (1)
| O52512 |
T2S1_STRFI
Streptomyces fimbriatus
Type-2 restriction enzyme SfiI
|
PDB Structure
| PDB | 2EZV |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
A view of consecutive binding events from structures of tetrameric endonuclease SfiI bound to DNA
Embo J.
|
