CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.600 | ECO RV Endonuclease; Chain A |
|
3.40.600.40 | Type II restriction enzyme SfiI, multifunctional domain |
Domain Context
CATH Clusters
| Superfamily | 3.40.600.40 |
| Functional Family |
Enzyme Information
| 3.1.21.4 |
Type II site-specific deoxyribonuclease.
based on mapping to UniProt O52512
Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.
-!- Large group of enzymes which recognize specific short DNA sequences and cleave either within, or at a short specific distance from, the recognition site. -!- See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/
|
UniProtKB Entries (1)
| O52512 |
T2S1_STRFI
Streptomyces fimbriatus
Type-2 restriction enzyme SfiI
|
PDB Structure
| PDB | 2EZV |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
A view of consecutive binding events from structures of tetrameric endonuclease SfiI bound to DNA
Embo J.
|
