CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family Dual specificity protein kinase CLK2

Enzyme Information

2.7.12.1
Dual-specificity kinase.
based on mapping to UniProt P49761
ATP + a protein = ADP + a phosphoprotein.
-!- This family of enzymes can phosphorylate both Ser/Thr and Tyr residues. -!- Formerly EC 2.7.1.37.

UniProtKB Entries (1)

P49761
CLK3_HUMAN
Homo sapiens
Dual specificity protein kinase CLK3

PDB Structure

PDB 2EU9
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Kinase domain insertions define distinct roles of CLK kinases in SR protein phosphorylation.
Bullock, A.N., Das, S., Debreczeni, J.E., Rellos, P., Fedorov, O., Niesen, F.H., Guo, K., Papagrigoriou, E., Amos, A.L., Cho, S., Turk, B.E., Ghosh, G., Knapp, S.
Structure