CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.40 | Beta Barrel |
|
2.40.50 | OB fold (Dihydrolipoamide Acetyltransferase, E2P) |
|
2.40.50.140 | Nucleic acid-binding proteins |
Domain Context
CATH Clusters
| Superfamily | Nucleic acid-binding proteins |
| Functional Family | ATP-dependent RNA helicase DHX8 |
Enzyme Information
| 3.6.4.13 |
RNA helicase.
based on mapping to UniProt Q14562
ATP + H(2)O = ADP + phosphate.
-!- RNA helicases utilize the energy from ATP hydrolysis to unwind RNA. -!- Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity. -!- Some helicases unwind DNA as well as RNA. -!- May be identical with EC 3.6.4.12 (DNA helicase).
|
UniProtKB Entries (1)
| Q14562 |
DHX8_HUMAN
Homo sapiens
ATP-dependent RNA helicase DHX8
|
PDB Structure
| PDB | 2EQS |
| External Links | |
| Method | SOLUTION NMR |
| Organism | |
| Primary Citation |
Solution structure of the S1 RNA binding domain of human ATP-dependent RNA helicase DHX8
To be Published
|