CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family

Enzyme Information

1.1.1.1
Alcohol dehydrogenase.
based on mapping to UniProt Q96XE0
(1) A primary alcohol + NAD(+) = an aldehyde + NADH. (2) A secondary alcohol + NAD(+) = a ketone + NADH.
-!- Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol. -!- The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.

UniProtKB Entries (1)

Q96XE0
ADH_SULTO
Sulfurisphaera tokodaii str. 7
NAD-dependent alcohol dehydrogenase

PDB Structure

PDB 2EER
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural study of Project ID ST2577 from Sulfolobus tokodaii strain7
Asada, Y., Kunishima, N.
To be Published